The Ultimate Guide To ceesdekker
The Ultimate Guide To ceesdekker
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‘Certainly, that may be about proper. I try to find a physical comprehension of Organic systems in the base-up way. I think you might distinguish a few lines of analysis in my team in the meanwhile. The main issues chromosome framework: how do you obtain a metre-very long DNA polymer folded and organised in this kind of microscopic cell? We've designed visualisation approaches that allow us to study how, one example is, SMC proteins loop DNA (online video on Youtube) in order to Construct up chromosomes.
1996, 1st mesoscopic demand density waves devices; and 1st electrical measurements on only one metal nanocluster amongst nanoelectrodes
Multicolor imaging from the bacterial nucleoid and mobile division proteins with blue, orange, and in close proximity to-infrared fluorescent proteins
Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.
This yielded a breakthrough. Inside of only some months, we have been able to evaluate transportation by means of somebody solitary-walled carbon nanotube. Dependant on minimal-temperature experiments by a superb PhD college student in my team, Sander Tans (now a valued colleague and professor at Delft University of Engineering having an Lively research lab at AMOLF in Amsterdam), we showed that carbon nanotubes had been real quantum wires with quite very long (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Microbiology has only existed for just a century, due to the fact we started to study micro-organisms more very seriously. I believed nanobiology was an proper term, for the reason that all molecular Organic related interactions occur with the nanoscale: a protein is several nanometres in size, DNA is two nm thick.’
We use nanofabricated microfluidic buildings to sample spatial boundaries ceesdekker.net for microorganisms and biomimetic vesicles with reconstituted protein networks and this assess the fundamental function of spatial confinement on the molecular and cellular level. Our jobs involve the subsequent:
He also observed time to write down various books, ship almost forty thousand tweets and direct A prosperous study team at Delft College of Technologies. ‘It doesn’t sense like work’, he states. ‘I’m just terribly curious.’
In 1993, being a youthful and keen associate professor at Delft University of Know-how, I had at first centered the research initiatives of my team on measuring the electrical conductance of a single conducting-polymer molecule. Inside of two yrs, we experienced produced a device through which only one wire of the phthalocyaninepolysiloxane polymer was connected among two carefully spaced steel nanoelectrodes.
At this time, we also realized that it ought to be probable to employ only one semiconducting carbon nanotube to help make a transistor — and we established out to make it. We stretched personal semiconducting nanotubes across metallic electrodes and used the fundamental silicon substrate to be a gate electrode, developing The essential 3-terminal layout of a industry-influence transistor (Fig.
Since 2000 he moved to single-molecule biophysics and nanobiology, with investigation from scientific studies of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Far more not long ago his investigate has centered on finding out chromatin composition and mobile division with bacteria on chip, when he can be aiming to in the end Construct synthetic cells from the bottom up.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart structure in 2005. (nl)